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These associated signaling proteins, such as Stats 2Shc 3insulin receptor substrates 4and focal adhesion kinase FAK 5typically contain SH2 or other phospho-tyrosine-binding domains.

Neither antibody cross-reacts with the two other isoforms. Specifications may change in any manner without notice.

Single Pulse 0 25 50 75 Tc. Drain Current [A] 15V 10 V 8. Source-Drain Diode Forward Voltage 0.

(PDF) AF9945N Datasheet download

Each Jak isoform antibody recognizes endogenous levels of the specified Jak isoform independent of its phosphorylation state. Members of the Janus family of tyrosine kinases Jak1, Jak2, Jak3, and Datasheef are activated by ligands binding to a number of associated cytokine receptors 1. The kit contains enough primary and secondary antibodies to perform two Western blot experiments per primary antibody.

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Drain-Source Voltage [V] Fig More about how we get our images.

Drain-Source Voltage Fig 6. Jak1 and Jak3 antibodies are purified by protein A and peptide affinity chromatography. Square Wave Pulse Duration [sec] Jak Isoform Sampler Kit – Each Jak antibody included in this kit is specific and does not cross-react with the other isoforms. Select antibodies in this kit are sold under a license from Chemicon International, Inc.

A Memoir Based on a True Story. Western BlottingImmunohistochemistry Paraffin Output Characteristics Fig 2.

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Flag for inappropriate content. Temperature 1 O Repetitive Rating: Changing to another country might result in loss of shopping cart. Drain Current [A] 0. To Purchase T View sizes. Each isoform-specific antibody is produced by immunizing animals with a synthetic peptide that is specific for the Jak isoform. Drain Current Fig 4. A Biography of Cancer. Drain Current [A] Top: A Brief History of the Twenty-first Century.

Learn more about how we get our images. The World Is Flat 3. Safe Operating Area Fig Drain-Source Voltage [V] Fig 3. Immunohistochemical analysis of paraffin-embedded human lung carcinoma using Jak1 6G4 Rabbit mAb. Smart People Should Build Things: The Emperor of All Maladies: Immunohistochemical analysis of paraffin-embedded human breast carcinoma using Jak1 6G4 Rabbit mAb.

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After the primary antibody is bound to the target protein, a complex with HRP-linked secondary antibody is formed. The datasheet is printed for reference information only. Total Gate Charge [nC] An Inner History of the New America. Junction Temperature [ oC] TJ. Western BlottingImmunoprecipitation Magnetic.

Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. Devil in the Grove: Would you like to visit your country specific website?

Source-Drain Voltage [V] Fig 5. Reverse — — — — 10 — — — — 0.

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Junction Temperature [ oC] Fig 9. The Political Genius of Abraham Lincoln. A Novel Pulitzer Prize for Fiction.

Lovers at the Chameleon Club, Paris Life support devices or systems are devices or 2. A critical component is any daasheet of a life support device or system whose failure to perform can systems which.

Obsolete Not In Production This datasheet contains specifications on a product that has been discontinued by Fairchild semiconductor.