An ameloblastic fibroma is a fibroma of the ameloblastic tissue, that is, an odontogenic tumor arising from the enamel organ or dental lamina. It may be either. Ameloblastic fibroma, is a mixed odontogenic tumor, which commonly affects young children under the age of 20 years, with the mandibular premolar-molar. ameloblastic fibroma in a 9-year-old boy has been presented along with a review of the literature. The tumor responded to conservative surgical treatment.

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Related articles Ameloblastic fibroma cytopathology fine-needle aspiration mandible. Author information Article notes Copyright and License information Disclaimer.

Fine needle aspiration did not yield any fluid ruling out a cystic lesion. As no hard tissue is observed, AF appearing as a mixed radiographic image is very unusual 4. It was first described by Kruse in and later classified as a separate entity by Thoma and Goldman in [ 23 ]. Odontogenic Tumors and Allied Lesions. Ameloblastic sarcoma of the mandible. How to cite this URL: Report of a case with a special reference to its aspiration cytologic findings. The posterior region of the mandible is the most affected site 3 – 5but large tumors may expand to anterior regions of the mandible.

Please review our privacy policy. Int J Oral Maxillofac Pathol ;2: It is more common in the first and second decades of life, when odontogenesis is ongoing, than in later decades.

The least differentiated lesion, ameloblastic fibroma, actually occurs, on average, at an older age then the more differentiated ameloblastic fibro-odontoma and odontoma [ 4 ]. Fine-needle aspiration cytologic smears showed two different types of cellular elements: Journal List Head Neck Pathol v. This is a case report of a year-old female with a swelling in the right posterior mandibular region since 4 months, which was subsequently diagnosed as ameloblastic fibroma.


Several spindle-shaped cells and abundant extracellular matrix deposition were found between the islands of neoplastic cells HE, x Advanced Search Users Online: However, the diagnosis of malignant transformation is only established from the retrieval of the primary tumor or recurring tumors in which the original histological features of the AF can be observed 1.

Diagnosis Histological evaluation revealed multiple fragments of richly cellular mesenchymal tissue containing round drop-like islands and long narrow anastomosing cords of odontogenic epithelium.

Basic Oral and Maxillofacial Pathology. In neoplastic cases, it may be labeled an ameloblastic fibrosarcoma in accord with the terminological distinction akeloblastic reserves the word fibroma for benign tumors and assigns the word fibrosarcoma to malignant ones. Enucleation of the tumor was performed, followed by curettage of the surrounding bone. Ameloblastic fibroma AF is an uncommon benign odontogenic tumour, with both epithelial and mesenchymal neoplastic proliferation.

Please review our privacy policy. Small fibromma are asymptomatic, while larger ones produce significant swelling of the jaws. The overlying mucosa was intact. Hamartoma or a true neoplasm. Both the swellings exhibited gradual increase in size with evidence of nasal blockage Figure 1. However, most of the cases of AFs are encountered as an incidental finding [ 910 ] reiterating their radiographic significance in the differential diagnosis with entities such as maeloblastic cyst, ameloblastoma, odontogenic keratocyst, and ameloblastic fibrosarcoma [ 1112 ].

Benign mixed odontogenic tumors. Additionally, in the current case, the tumor was located between the roots of the left mandibular second premolar and first molar, causing a diastema between these teeth. The surgical specimen was then sent for histopathological analysis. Fibrom needle aspiration biopsy.

Ameloblastic Fibroma

Histopathology alone is usually not enough to differentiate neoplastic cases from hamartomatous ones, because the histology is very similar. Orthopantomogram showing ame,oblastic well-defined, noncorticated solitary unilocular radiolucency in 45, 46, and 47 region Click here to view. A conservative approach, with excision followed by curettage, as performed fibromma the present case, appears to be the ajeloblastic adequate treatment 3.


Nevertheless, approximately two thirds of the ameloblastic fibrosarcomas representing malignant tumors de novo 8. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author s and source are credited.

The radiopaque foci in these mixed tumors usually are cen-trally located or distributed amelblastic entire lesion. There are no conflicts of interest. However, the presence of ulceration and pain does not exclude the diagnosis of AF, as these symptoms have been reported in an extensive review carried out by Chen et al. View at Google Scholar C. The surgical specimen was fixed in formalin and sent for histopathological analysis, which revealed an odontogenic tumor formed by islands of epithelial cells, with the columnar peripheral cells showing nucleus in inverted polarization.

The epithelial islands, nests, and strands fibrona composed of peripheral tall columnar hyperchromatic cells exhibiting reversal of polarity and loosely arranged central cells having angular to spindle shape.

Ameloblastic fibroma

Text book of oral and maxillofacial pathology; pp. Panoramic radiograph showed a unilocular radiolucent area with well-defined borders, involving the posterior aspect of the right mandible. Although it is rare, malignant transformation may occur, mainly in recurrent tumors 78.

Treatment of large ameloblastic fibroma: Because of AF is often associated with non-erupted teeth, it ameloblastiv initially be interpreted as a dentigerous cyst 12.

If a tooth is associated with the lesion it may accompany the specimen.

Abstract Ameloblastic fibroma AF is an uncommon benign odontogenic tumour, with both epithelial and mesenchymal neoplastic proliferation.