ABSTRACT. The present study aimed to evaluate the in vitro antimicrobial activity of pharmacologically important Adhatoda vasica plant extracts. Plant Adhatoda vasica L. Nees (Acanthaceae) commonly known as Malabar nut is an evergreen two – three m tall shrub, sometime used as. Adhatoda vasica (L.) (Acanthaceae) is used in the indigenous system of medicine in India. The alkaloid Vasicine was isolated from ethanolic extract of the .
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Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper
International Journal of Cancer. The structure was elucidated using spectroscopic methods: Then the residue was crystallised from chloroform to get Vasicine acetate as colorless crystals m.
Zones of inhibition were recorded in millimetres and the experiment was repeated twice. The radical scavenging activity of Vasicine acetate at different concentrations is shown in Table 3. The combined chloroform extract was washed with water, vaxica, and dried over anhydrous sodium sulphate. International Journal of Crude Drug Research. Published online Jan Antimicrobial Activity Antibacterial and antifungal activities were carried out using disc diffusion method [ 16 ].
Journal List Biomed Res Int v. The required concentrations, Cytotoxicity of each sample was expressed as IC 50 value.
Antibacterial activity of adhatoda vasica leaf extract
Classical Uses of Medicinal Plants. Journal of Obstetrics and Gynaecology of India. The estimation afhatoda Vasicine acetate content in the extract was performed using linear regression analysis.
BoxRiyadhSaudi Arabia. The column was eluted with chloroform and chloroform: The compound showed prominent cytotoxic activity in vitro against A lung adenocarcinoma cancer cell line.
The physical and spectroscopic data were compared with those reported in the literature [ 15 ]. Potent uterine activity of alkaloid vasicine. Ray of hope for cancer patients.
The solutions were filtered through a membrane filter pore size 0. Materials and Methods 2.
The leaves qctivity used to treat malarial fever, chronic fever, intrinsic hemorrhage, cough, asthma, leprosy, skin diseases, and piles [ 6 ]. International Journal of Green Pharmacy.
Antibacterial Activity of Leaf Extracts of Adhatoda vasica – MAHE Digital Repository
Vasicine showed antimicrobial activity against S. BHT is used as standard of antioxidant. In the present communication we report the antimicrobisl, antioxidant, and anticancer effects of Vasicine acetate acetylated from Vasicine obtained from A. Minimum inhibitory concentration studies of the compounds were performed according to the standard reference methods for bacteria [ 17 ] and filamentous fungi [ 18 ]. Kulkarni [ 24 ] reported that A.
The worldwide threat of antimicrobial resistance. Council of Scientific and Industrial Research; The cytotoxicity was determined according to the method of Balachandran et al. The plant is reported to show abortifacient [ 7 ], antimicrobial [ 89 ], and antitussive activities [ 10 ].
B revised New Delhi, India: Clinical and Laboratory Standards Institute; The free radical scavenging activity was calculated as follows:. Minimum Inhibitory Concentration MIC Minimum inhibitory concentration studies of the compounds were performed according to the standard reference methods for bacteria [ 17 ] and filamentous fungi [ 18 ].
Al-Dhabi1 C. Vasicine is reported to have bronchodilatory, respiratory stimulant, and uterine stimulant effects [ 14 ]. The fraction was further purified and the compound Vasicine was isolated. National Center for Biotechnology InformationU.