Request PDF on ResearchGate | On Jan 1, , S.D. Navaneethan and others published Inhibidores de la HMG CoA reductasa (estatinas) para pacientes en. Request PDF on ResearchGate | On Jan 1, , S.D. Navaneethan and others published Inhibidores de la HMG CoA reductasa (estatinas) para pacientes con. Los inhibidores de la enzima hepática HMG-CoA reductasa (estatinas), pueden indu- cir importantes reducciones en los niveles de colesterol plasmático y por.

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J Acquir Immune Defic Syndr.

Basic Clin Pharmacol Toxicol. Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine. J R Coll Physicians Edinb. Effect of efavirenz on the pharmacokinetics of simvastatin, atorvastatin, and pravastatin: Por ello, las estatinas metabolizadas por la CYP3A4 como la simvastatina, lovastatina y atorvastatina son las estatinas que presentan mayor evidencia sobre las interacciones, mientras que la pravastatina posee un mejor perfil de seguridad debido a que no es metabolizado por CYP Progress in Cardiovascular Diseases 41 2: Possible colchicine rhabdomyolysis in a fluvastatin-treated patient.

Most of these interactions are attributed to simultaneous use of CYP3A4 inhibitors. Breast Cancer Res Treat. Pharmacodynamic interaction between ezetimibe and rosuvastatin. Interaction between enfuvirtide, an injectable fusion inhibitor, and niacin in an HIV-infected patient.

Effect of rifampicin on pravastatin pharmacokinetics in healthy subjects. Rhabdomyolysis resulting from interaction of simvastatin and clarithromycin demonstrated by Tcm MDP scintigraphy. Rosuvastatin has been studied at doses ranging from 1 to 80 mg.


Warfarin potentiation with bezafibrate. A lesson for everyone in drug-drug interactions.

HMG-CoA reductasa

Effect ofcolesevelam on lovastatin pharmacokinetics. Fibrates in the treatment of dyslipidemias-time for a reassessment. Different effects of St John’s wort on the pharmacokinetics of simvastatin and hng-coa. Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: Applied Microbiology and Biotechnology 77 5: The effect of fluvastatin on the pharmacokinetics and pharmacodynamics of ezetimibe. Effects of ezetimibe on cyclosporine pharmacokinetics in healthy subjects.

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Rapid onset of muscle weakness rhabdomyolysis associated with the combined use of simvastatin and colchicine. Drug Metabol Drug Interact. Shitara Y, Sugiyama Y. Rhabdomyolysis after concomitant use of cyclosporine, simvastatin, gemfibrozil, and itraconazole. Pharmacokinetics and pharmacodynamics of fluvastatin in heart transplant recipients taking cyclosporine A. Cimetidine does not alter inhibiores pharmacokinetics or LDL-cholesterol reduction. Lack of a clinically significant pharmacokinetic interaction between fenofibrate and pravastatin in healthy volunteers.

Elimination of alfentanil delivered by infusion is not altered by the chronic administration of atorvastatin. Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: Acute renal failure with the combined use of rosuvastatin and fenofibrate.

Concomitant use of simvastatin and amiodarone resulting in severe rhabdomyolysis: Interaction of single-dose ezetimibe and steady-state cyclosporine in renal transplant patients.

HMG-CoA reductasa – Wikipedia, la enciclopedia libre

Effects of concomitant therapy with diltiazem on the lipid responses to simvastatin in Chinese subjects. High incidence of reduced plasma HDL cholesterol in diabetic patients treated with rosiglitazone and fibrate. Rhabdomyolysis secondary to interaction of fusidic acid and simvastatin. Rhabdomyolysis associated with concomitant use of atorvastatin and cyclosporine. Evaluation of the pharmacokinetic interaction between fluvastatin XL and cyclosporine in renal transplant recipients.


Study of the drug-drug interaction between simvastatin and cisapride in man. A prospective study in renal transplant patients. A case report of acute hmg-cox induced by concomitant use of colchicine and bezafibrate.


The Journal of Cell Biology 5: El ezetimiba inhibixores bien tolerado y no interacciona con fluvastatinalovastatinarosuvastatina o simvastatina J Pharmacol Exp Ther. Pharmacokinetic interaction between isradipine and lovastatin in normal, female and male volunteers. Am J Cardiol ;96 suppl inibidores Archives of Biochemistry and Biophysics 2: Enferm Infecc Microbiol Clin.

Pharmacokinetic drug interaction between gemfibrozil and sitagliptin in healthy Indian male volunteers. Effects of imatinib mesylate STI, Glivec on the pharmacokinetics of simvastatin, a cytochrome p 3A4 substrate, in patients with chronic myeloid leukaemia. Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin.

Rhabdomyolysis caused by simvastatinin a patient following heart transplantation and cyclosporine therapy.